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Dupilumab improves lung function in patients with uncontrolled, moderate-to-severe asthma

BACKGROUND: Dupilumab, a fully human monoclonal antibody, blocks the shared receptor component for interleukin-4 and interleukin-13, key drivers of type 2 inflammation. In the phase 3 LIBERTY ASTHMA QUEST trial (NCT02414854) in patients with uncontrolled, moderate-to-severe asthma, add-on dupilumab...

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Bibliografske podrobnosti
izdano v:ERJ Open Res
Main Authors: Castro, Mario, Rabe, Klaus F., Corren, Jonathan, Pavord, Ian D., Katelaris, Constance H., Tohda, Yuji, Zhang, Bingzhi, Rice, Megan S., Maroni, Jaman, Rowe, Paul, Pirozzi, Gianluca, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Graham, Neil M.H., Teper, Ariel
Format: Artigo
Jezik:Inglês
Izdano: European Respiratory Society 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983496/
https://ncbi.nlm.nih.gov/pubmed/32010719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00204-2019
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