Dupilumab is effective in type 2‐high asthma patients receiving high‐dose inhaled corticosteroids at baseline

BACKGROUND: Dupilumab blocks the shared receptor component for interleukin (IL)‐4/IL‐13, key drivers of type 2 inflammation. In phase 2b (NCT01854047) and phase 3 LIBERTY ASTHMA QUEST (NCT02414854), add‐on dupilumab 200/300 mg every 2 weeks (q2w) reduced severe exacerbations, improved prebronchodila...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Allergy
Prif Awduron: Bourdin, Arnaud, Papi, Alberto A., Corren, Jonathan, Virchow, J. Christian, Rice, Megan S., Deniz, Yamo, Djandji, Michel, Rowe, Paul, Pavord, Ian D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
ORIGINAL ARTICLES
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820970/
https://ncbi.nlm.nih.gov/pubmed/33010038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14611
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