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Loss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAs
Loss of the tumor suppressor tuberous sclerosis complex 1 (Tsc1) in the liver promotes gluconeogenesis and glucose intolerance. We asked whether this could be attributed to aberrant expression of small RNAs. We performed small-RNA sequencing on liver of Tsc1-knockout mice, and found that miRNAs of t...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6983401/ https://ncbi.nlm.nih.gov/pubmed/31919282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918931117 |
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