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The Upregulation of Genomic Imprinted DLK1-Dio3 miRNAs in Murine Lupus Is Associated with Global DNA Hypomethylation

Epigenetic factors such as DNA methylation and microRNAs (miRNAs) are now increasingly recognized as vital contributors to lupus etiology. In this study, we investigated the potential interaction of these two epigenetic factors in lupus-prone MRL-lpr mice. We recently reported dysregulated expressio...

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Publicat a:PLoS One
Autors principals: Dai, Rujuan, Lu, Ran, Ahmed, S. Ansar
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829153/
https://ncbi.nlm.nih.gov/pubmed/27070142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153509
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