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Improved protein structure prediction using predicted interresidue orientations

The prediction of interresidue contacts and distances from coevolutionary data using deep learning has considerably advanced protein structure prediction. Here, we build on these advances by developing a deep residual network for predicting interresidue orientations, in addition to distances, and a...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Yang, Jianyi, Anishchenko, Ivan, Park, Hahnbeom, Peng, Zhenling, Ovchinnikov, Sergey, Baker, David
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983395/
https://ncbi.nlm.nih.gov/pubmed/31896580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914677117
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