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The effector mechanism of siRNA spherical nucleic acids

Spherical nucleic acids (SNAs) are nanostructures formed by chemically conjugating short linear strands of oligonucleotides to a nanoparticle template. When made with modified small interfering RNA (siRNA) duplexes, SNAs act as single-entity transfection and gene silencing agents and have been used...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Yamankurt, Gokay, Stawicki, Robert J., Posadas, Diana M., Nguyen, Joseph Q., Carthew, Richard W., Mirkin, Chad A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983385/
https://ncbi.nlm.nih.gov/pubmed/31900365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915907117
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