MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract

While the bioinformatics resource-tool iSyTE (integrated Systems Tool for Eye gene discovery) effectively identifies human cataract-associated genes, it is currently based on just transcriptome data, and thus it is necessary to include protein-level information to gain greater confidence in gene pri...

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Detalhes bibliográficos
Publicado no:Hum Genet
Main Authors: Aryal, Sandeep, Anand, Deepti, Hernandez, Francisco G., Weatherbee, Bailey A. T., Huang, Hongzhan, Reddy, Ashok P., Wilmarth, Phillip A., David, Larry L., Lachke, Salil A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983357/
https://ncbi.nlm.nih.gov/pubmed/31797049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-019-02095-5
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