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Classifying melanoma by TERT promoter mutational status

While TERT promoter mutations have been associated with a worsened prognosis in melanoma, the relationship between mutation status and downstream telomerase activity and telomere length remains convoluted. Using Sanger sequencing and qPCR-based techniques, we evaluated 60 melanoma cell lines for TER...

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Publicat a:J Invest Dermatol
Autors principals: Shaughnessy, Michael, Njauw, Ching-Ni, Artomov, Mykyta, Tsao, Hensin
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983338/
https://ncbi.nlm.nih.gov/pubmed/31425705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2019.06.149
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