A Triazole Hybrid of Neolignans as a Potential Antileishmanial Agent by Triggering Mitochondrial Dysfunction

In the search for new compounds with antileishmanial activity, we synthesized a triazole hybrid analogue of the neolignans grandisin and machilin G (LASQUIM 25), which was previously found highly active against both promastigotes and intracellular amastigote forms of Leishmania amazonensis. In this...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cardozo Pinto de Arruda, Carla, de Jesus Hardoim, Daiana, Silva Rizk, Yasmin, da Silva Freitas de Souza, Celeste, Zaverucha do Valle, Tânia, Bento Carvalho, Diego, Nosomi Taniwaki, Noemi, de Morais Baroni, Adriano Cesar, da Silva Calabrese, Kátia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983227/
https://ncbi.nlm.nih.gov/pubmed/31861910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010037
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