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On the Reversible and Irreversible Inhibition of Rhodesain by Curcumin

Previously, it was suggested that the natural compound curcumin is an irreversible inhibitor of rhodesain, the major lysosomal cysteine protease of the protozoan parasite Trypanosoma brucei. The suggestion was based on a time-dependent inhibition of the enzyme by curcumin and a lack of recovery of a...

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Detalhes bibliográficos
Publicado no:Molecules
Autor principal: Steverding, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983121/
https://ncbi.nlm.nih.gov/pubmed/31905815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010143
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