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Modeling the Antileukemia Activity of Ellipticine-Related Compounds: QSAR and Molecular Docking Study

The antileukemia cancer activity of organic compounds analogous to ellipticine representes a critical endpoint in the understanding of this dramatic disease. A molecular modeling simulation on a dataset of 23 compounds, all of which comply with Lipinski’s rules and have a structure analogous to elli...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Márquez, Edgar, Mora, José R., Flores-Morales, Virginia, Insuasty, Daniel, Calle, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982814/
https://ncbi.nlm.nih.gov/pubmed/31861689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010024
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