MOLECULAR MODELLING, 3D-QSAR, AND DRUG DOCKING STUDIES ON THE ROLE OF NATURAL ANTICOAGULANT COMPOUNDS IN ANTITHROMBOTIC THERAPY

Thromboembolic disorders are the leading cause of human mortality. Therefore, development of effective anticoagulant therapy is critical. Factor XIIIA (FXIIIA) protein is a crucial factor in the blood coagulation cascade, and hence it is a vital target for evolution of new antithrombotic agents. Str...

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Vydáno v:Int J Pharm Sci Res
Hlavní autoři: Kakarla, Prathusha, Devireddy, Amith R., Inupakutika, Madhuri A., Cheeti, Upender R., Floyd, Jared T., Mun, Mukherjee M., Vigil, Raelyn N., Hunter, Russell P., Varela, Manuel F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347951/
https://ncbi.nlm.nih.gov/pubmed/25750914
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