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Artificial signaling in mammalian cells enabled by prokaryotic two-component system
Augmenting live cells with novel signal transduction capabilities is a key objective in genetic engineering and synthetic biology. We showed earlier that two-component signaling pathways could function in mammalian cells, albeit while losing their ligand sensitivity. Here we show how to transduce sm...
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| Veröffentlicht in: | Nat Chem Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6982536/ https://ncbi.nlm.nih.gov/pubmed/31844302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0429-9 |
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