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An Imatinib–non‐responsive patient with an ABL Leu387Trp mutation achieves cytogenetic and molecular response under bosutinib: Case report and biological characterization

Leu387Trp mutation, aroused in an imatinib‐non‐responsive CML patient, was selected by imatinib treatment along with other unknown factors responsible for resistance, and then it was overcome by bosutinib. These results will be useful for treating patients with this rare mutation and will advise aga...

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Detalhes bibliográficos
Publicado no:Clin Case Rep
Main Authors: Crespiatico, Ilaria, Bossi, Elisa, Brioschi, Filippo, Piazza, Rocco, Mologni, Luca, Gambacorti‐Passerini, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982521/
https://ncbi.nlm.nih.gov/pubmed/31998490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.2531
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