Hypomethylation of nerve growth factor (NGF) promotes binding of C/EBPα and contributes to inflammatory hyperalgesia in rats

BACKGROUND: Chronic pain usually accompanied by tissue damage and inflammation. However, the pathogenesis of chronic pain remains unclear. METHODS: We investigated the role of nerve growth factor (NGF) in chronic inflammatory pain induced by complete Freund’s adjuvant (CFA), explored the methylation...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Yuan, Hongjie, Du, Shibin, Chen, Liping, Xu, Xiaoqing, Wang, Yufeng, Ji, Fuhai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982391/
https://ncbi.nlm.nih.gov/pubmed/31980031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-1711-1
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