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Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function

The members of Rho family of GTPases, RhoA and Rac1 regulate endothelial cytoskeleton dynamics and hence barrier integrity. The spatial activities of these GTPases are regulated by post-translational prenylation. In the present study, we investigated the effect of prenylation inhibition on the endot...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Aslam, Muhammad, Troidl, Christian, Tanislav, Christian, Rohrbach, Susanne, Gündüz, Dursun, Hamm, Christian W.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981884/
https://ncbi.nlm.nih.gov/pubmed/31861297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010002
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