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Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function

The members of Rho family of GTPases, RhoA and Rac1 regulate endothelial cytoskeleton dynamics and hence barrier integrity. The spatial activities of these GTPases are regulated by post-translational prenylation. In the present study, we investigated the effect of prenylation inhibition on the endot...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Aslam, Muhammad, Troidl, Christian, Tanislav, Christian, Rohrbach, Susanne, Gündüz, Dursun, Hamm, Christian W.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981884/
https://ncbi.nlm.nih.gov/pubmed/31861297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010002
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