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Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function

The members of Rho family of GTPases, RhoA and Rac1 regulate endothelial cytoskeleton dynamics and hence barrier integrity. The spatial activities of these GTPases are regulated by post-translational prenylation. In the present study, we investigated the effect of prenylation inhibition on the endot...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Aslam, Muhammad, Troidl, Christian, Tanislav, Christian, Rohrbach, Susanne, Gündüz, Dursun, Hamm, Christian W.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981884/
https://ncbi.nlm.nih.gov/pubmed/31861297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010002
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