Interactions of Cisplatin and Daunorubicin at the Chromatin Level

Unexpectedly, the widely used anticancer agents Cisplatin (Cis-Pt) and Daunorubicin (Dauno) exhibited cell type- and concentration-dependent synergy or antagonism in vitro. We attempted to interpret these effects in terms of the changes elicited by the drugs in the chromatin, the target held primari...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Firouzi Niaki, Erfaneh, Van Acker, Thibaut, Imre, László, Nánási, Péter, Tarapcsák, Szabolcs, Bacsó, Zsolt, Vanhaecke, Frank, Szabó, Gábor
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981277/
https://ncbi.nlm.nih.gov/pubmed/31980698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57702-7
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