YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells

Fibroblastic reticular cells (FRCs) are immunologically specialized myofibroblasts of lymphoid organ, and FRC maturation is essential for structural and functional properties of lymph nodes (LNs). Here we show that YAP and TAZ (YAP/TAZ), the final effectors of Hippo signaling, regulate FRC commitmen...

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Publicado en:Nat Commun
Main Authors: Choi, Sung Yong, Bae, Hosung, Jeong, Sun-Hye, Park, Intae, Cho, Hyunsoo, Hong, Seon Pyo, Lee, Da-Hye, Lee, Choong-kun, Park, Jin-Sung, Suh, Sang Heon, Choi, Jeongwoon, Yang, Myung Jin, Jang, Jeon Yeob, Onder, Lucas, Moon, Jeong Hwan, Jeong, Han-Sin, Adams, Ralf H., Kim, Jin-Man, Ludewig, Burkhard, Song, Joo-Hye, Lim, Dae-Sik, Koh, Gou Young
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981200/
https://ncbi.nlm.nih.gov/pubmed/31980640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14293-1
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