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Adaptive Landscape Shaped by Core Endogenous Network Coordinates Complex Early Progenitor Fate Commitments in Embryonic Pancreas

The classical development hierarchy of pancreatic cell fate commitments describes that multipotent progenitors (MPs) first bifurcate into tip cells and trunk cells, and then these cells give rise to acinar cells and endocrine/ductal cells separately. However, lineage tracings reveal that pancreatic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Junqiang, Yuan, Ruoshi, Zhu, Xiaomei, Ao, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981170/
https://ncbi.nlm.nih.gov/pubmed/31980678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57903-0
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