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Cross-reactivity with self-antigen tunes the functional potential of naïve B cells specific for foreign antigens

Upon antigen exposure, naïve B cells expressing B cell receptors (BCR) able to bind antigen can undergo robust proliferation and differentiation that can result in the production of antibody-secreting and memory B cells. The factors determining whether an individual naïve B cell will proliferate fol...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Steach, Holly R., DeBuysscher, Blair L., Schwartz, Allison, Boonyaratanakornkit, Jim, Baker, Melissa L., Tooley, Marti R., Pease, Nicholas A., Taylor, Justin J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981075/
https://ncbi.nlm.nih.gov/pubmed/31882518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900799
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