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Notch Signaling Regulates Antigen Sensitivity of Naive CD4(+) T Cells by Tuning Co-stimulation
Adaptive immune responses begin when naive CD4(+) T cells engage peptide+major histocompatibility complex class II and co-stimulatory molecules on antigen-presenting cells (APCs). Notch signaling can influence effector functions in differentiated CD4(+) T helper and T regulatory cells. Whether and h...
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| Publié dans: | Immunity |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4314725/ https://ncbi.nlm.nih.gov/pubmed/25607460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.12.027 |
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