CD73-Dependent Adenosine Dampens Interleukin 1β-Induced CXCL8 Production in Gingival Fibroblasts: Association with Heme Oxygenase-1 (HO-1) And Adenosine Monophosphate–Activated Protein Kinase (AMPK)

BACKGROUND: During inflammation, stressed or infected cells can release adenosine tri-phosphate (ATP) to the extracellular medium, which can be hydrolyzed to adenosine by ectonucleotidases such as ectonucleoside triphosphate diphosphohydrolase 1 (CD39) and 5’ –nucleotidase (CD73). The role of CD73 i...

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Publicado no:J Periodontol
Main Authors: Ramos-Junior, Erivan Schnaider, Pedram, Michael, Lee, Renee E., Exstrom, Drake, Yilmaz, Özlem, Coutinho-Silva, Robson, Ojcius, David M., Morandini, Ana Carolina
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980930/
https://ncbi.nlm.nih.gov/pubmed/31347162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JPER.19-0137
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