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Porphyromonas gingivalis Fimbriae Dampen P2X7-Dependent Interleukin-1β Secretion
Porphyromonas gingivalis is a major contributor to the pathogenesis of periodontitis, an infection-driven inflammatory disease that leads to bone destruction. This pathogen stimulates pro-interleukin (IL)-1β synthesis but not mature IL-1β secretion, unless the P2X7 receptor is activated by extracell...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
S. Karger AG
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201861/ https://ncbi.nlm.nih.gov/pubmed/24925032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363338 |
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