Porphyromonas gingivalis Fimbriae Dampen P2X7-Dependent Interleukin-1β Secretion

Porphyromonas gingivalis is a major contributor to the pathogenesis of periodontitis, an infection-driven inflammatory disease that leads to bone destruction. This pathogen stimulates pro-interleukin (IL)-1β synthesis but not mature IL-1β secretion, unless the P2X7 receptor is activated by extracell...

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Hlavní autoři: Morandini, Ana Carolina, Ramos-Junior, Erivan S., Potempa, Jan, Nguyen, Ky-Anh, Oliveira, Ana Carolina, Bellio, Maria, Ojcius, David M., Scharfstein, Julio, Coutinho-Silva, Robson
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201861/
https://ncbi.nlm.nih.gov/pubmed/24925032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363338
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