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Tonic calcium-activated chloride current sustained by ATP release and highly desensitizing human P2X1 receptors

Extracellular adenosine triphosphate (ATP) participates in maintaining the vascular tone in the CNS, particularly in the retina, via the tonic activity of ligand gated activated P2X1 receptors. P2X1 receptors are characterized by their high affinity for ATP and their strong desensitization to concen...

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Pubblicato in:Neuroscience
Autori principali: Limon, Agenor, Hagopian, Garo, Reyes-Ruiz, Jorge M., Miledi, Ricardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980929/
https://ncbi.nlm.nih.gov/pubmed/31349005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.07.025
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