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Loss of functional GABA(A) receptors in the Alzheimer diseased brain

The cholinergic and glutamatergic neurotransmission systems are known to be severely disrupted in Alzheimer's disease (AD). GABAergic neurotransmission, in contrast, is generally thought to be well preserved. Evidence from animal models and human postmortem tissue suggest GABAergic remodeling i...

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Hlavní autoři: Limon, Agenor, Reyes-Ruiz, Jorge Mauricio, Miledi, Ricardo
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382476/
https://ncbi.nlm.nih.gov/pubmed/22691495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204606109
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