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Loss of functional GABA(A) receptors in the Alzheimer diseased brain

The cholinergic and glutamatergic neurotransmission systems are known to be severely disrupted in Alzheimer's disease (AD). GABAergic neurotransmission, in contrast, is generally thought to be well preserved. Evidence from animal models and human postmortem tissue suggest GABAergic remodeling i...

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Autori principali: Limon, Agenor, Reyes-Ruiz, Jorge Mauricio, Miledi, Ricardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382476/
https://ncbi.nlm.nih.gov/pubmed/22691495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204606109
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