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Molecular Targeting of Immunosuppressants Using a Bifunctional Elastin-Like Polypeptide

Elastin-Like Polypeptides (ELP) are environmentally-responsive protein polymers which are easy to engineer and biocompatible, making them ideal candidates as drug carriers. Our team has recently utilized ELPs fused to FKBP12 to carry Rapamycin (Rapa), a potent immunosuppressant. Through high affinit...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Ju, Yaping, Guo, Hao, Yarber, Frances, Edman, Maria C., Peddi, Santosh, Janga, Srikanth Reddy, MacKay, J. Andrew, Hamm-Alvarez, Sarah F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980866/
https://ncbi.nlm.nih.gov/pubmed/31408605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00462
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