Bifunctional Elastin-like Polypeptide Nanoparticles Bind Rapamycin and Integrins and Suppress Tumor Growth in Vivo

Recombinant protein–polymer scaffolds such as elastin-like polypeptides (ELPs) offer drug-delivery opportunities including biocompatibility, monodispersity, and multifunctionality. We recently reported that the fusion of FK-506 binding protein 12 (FKBP) to an ELP nanoparticle (FSI) increases rapamyc...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Dhandhukia, Jugal P., Shi, Pu, Peddi, Santosh, Li, Zhe, Aluri, Suhaas, Ju, Yaping, Brill, Dab, Wang, Wan, Janib, Siti M., Lin, Yi-An, Liu, Shuanglong, Cui, Honggang, MacKay, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779105/
https://ncbi.nlm.nih.gov/pubmed/28937754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00469
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