A carregar...
The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells
The Bcl-2 family BH3 protein Bim promotes apoptosis at mitochondria by activating the pore-forming proteins Bax and Bak and by inhibiting the anti-apoptotic proteins Bcl-XL, Bcl-2 and Mcl-1. Bim binds to these proteins via its BH3 domain and to the mitochondrial membrane by a carboxyl-terminal seque...
Na minha lista:
| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6980855/ https://ncbi.nlm.nih.gov/pubmed/31976859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44525 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|