Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites

Triosephosphate isomerases (TPIs) from Taenia solium (TsTPI) and Schistosoma mansoni (SmTPI) are potential vaccine and drug targets against cysticercosis and schistosomiasis, respectively. This is due to the dependence of parasitic helminths on glycolysis and because those proteins elicit an immune...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Jimenez-Sandoval, Pedro, Castro-Torres, Eduardo, González-González, Rogelio, Díaz-Quezada, Corina, Gurrola, Misraim, Camacho-Manriquez, Laura D., Leyva-Navarro, Lucia, Brieba, Luis G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980832/
https://ncbi.nlm.nih.gov/pubmed/31923219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007815
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