Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites

Triosephosphate isomerases (TPIs) from Taenia solium (TsTPI) and Schistosoma mansoni (SmTPI) are potential vaccine and drug targets against cysticercosis and schistosomiasis, respectively. This is due to the dependence of parasitic helminths on glycolysis and because those proteins elicit an immune...

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Detaylı Bibliyografya
Yayımlandı:PLoS Negl Trop Dis
Asıl Yazarlar: Jimenez-Sandoval, Pedro, Castro-Torres, Eduardo, González-González, Rogelio, Díaz-Quezada, Corina, Gurrola, Misraim, Camacho-Manriquez, Laura D., Leyva-Navarro, Lucia, Brieba, Luis G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980832/
https://ncbi.nlm.nih.gov/pubmed/31923219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007815
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