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Immunogenicity of the Lyme Disease Antigen OspA, Particleized by Cobalt Porphyrin-Phospholipid Liposomes

Outer surface protein A (OspA) is a Borrelia lipoprotein and an established Lyme disease vaccine target. Admixing non-lipidated, recombinant B. burgdorferi OspA with liposomes containing cobalt porphyrin-phospholipid (CoPoP) resulted in rapid, particulate surface display of the conformationally inta...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Federizon, Jasmin, Frye, Amber, Huang, Wei-Chiao, Hart, Thomas M., He, Xuedan, Beltran, Christopher, Marcinkiewicz, Ashley L., Mainprize, Iain L., Wills, Melanie K. B., Lin, Yi-Pin, Lovell, Jonathan F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980772/
https://ncbi.nlm.nih.gov/pubmed/31727504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.10.073
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