Porphyrin-Phospholipid Liposomes with Tunable Leakiness

Drug bioavailability is a key consideration for drug delivery systems. When loaded with doxorubicin, liposomes containing 5 molar % porphyrin-phospholipid (HPPH liposomes) exhibited in vitro and in vivo serum stability that could be fine-tuned by varying the drug-to-lipid ratio. A higher drug loadin...

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Pubblicato in:J Control Release
Autori principali: Luo, Dandan, Carter, Kevin A, Razi, Aida, Geng, Jumin, Shao, Shuai, Lin, Cuiyan, Ortega, Joaquin, Lovell, Jonathan F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688124/
https://ncbi.nlm.nih.gov/pubmed/26578438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.11.011
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