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Metal Chelation Modulates Phototherapeutic Properties of Mitoxantrone-loaded Porphyrin–Phospholipid Liposomes

Liposomes incorporating porphyrin–phospholipid (PoP) can be formulated to release entrapped contents in response to near infrared (NIR) laser irradiation. Here, we examine effects of chelating copper or zinc into the PoP. Cu(II) and Zn(II) PoP liposomes, containing 10 molar % HPPH-lipid, exhibited u...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Principais autores: Carter, Kevin A., Wang, Sophie, Geng, Jumin, Luo, Dandan, Shao, Shuai, Lovell, Jonathan F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247800/
https://ncbi.nlm.nih.gov/pubmed/26691879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00653
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