Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration

Prostate embryonic development, pubertal and adult growth, maintenance, and regeneration are regulated through androgen signaling-mediated mesenchymal-epithelial interactions. Specifically, the essential role of mesenchymal androgen signaling in the development of prostate epithelium has been observ...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Le, Vien, He, Yongfeng, Aldahl, Joseph, Hooker, Erika, Yu, Eun-Jeong, Olson, Adam, Kim, Won Kyung, Lee, Dong-Hoon, Wong, Monica, Sheng, Ruoyu, Mi, Jiaqi, Geradts, Joseph, Cunha, Gerald R., Sun, Zijie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980684/
https://ncbi.nlm.nih.gov/pubmed/31929563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008588
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