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A non-amyloid prion particle that activates a heritable gene expression program
Spatiotemporal gene regulation is often driven by RNA-binding proteins that harbor long intrinsically disordered regions in addition to folded RNA-binding domains. We report that the disordered region of the evolutionarily ancient developmental regulator Vts1/Smaug drives self-assembly into gel-like...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6980676/ https://ncbi.nlm.nih.gov/pubmed/31757755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.028 |
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