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Hypothalamic Orexin and Mechanistic Target of Rapamycin Activation Mediate Sleep Dysfunction in a Mouse Model of Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is a genetic disease related to hyperactivation of the mechanistic target of rapamycin (mTOR) pathway and manifested by neurological symptoms, such as epilepsy and sleep disorders. The pathophysiology of sleep dysfunction is poorly understood and is likely multifacto...
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| Gepubliceerd in: | Neurobiol Dis |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6980650/ https://ncbi.nlm.nih.gov/pubmed/31605778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104615 |
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