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Dominant negative effects by inactive Spa47 mutants inhibit T3SS function and Shigella virulence
Type three secretion systems (T3SS) are complex nano-machines that evolved to inject bacterial effector proteins directly into the cytoplasm of eukaryotic cells. Many high-priority human pathogens rely on one or more T3SSs to cause disease and evade host immune responses, underscoring the need to be...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6980540/ https://ncbi.nlm.nih.gov/pubmed/31978132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228227 |
| Oznake: |
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