Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation

Like many Gram-negative pathogens, Shigella rely on a complex type III secretion system (T3SS) to inject effector proteins into host cells, take over host functions, and ultimately establish infection. Despite these critical roles, the energetics and regulatory mechanisms controlling the T3SS and pa...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Burgess, Jamie L., Burgess, R. Alan, Morales, Yalemi, Bouvang, Jenna M., Johnson, Sean J., Dickenson, Nicholas E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207059/
https://ncbi.nlm.nih.gov/pubmed/27770024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755256
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