Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation

Like many Gram-negative pathogens, Shigella rely on a complex type III secretion system (T3SS) to inject effector proteins into host cells, take over host functions, and ultimately establish infection. Despite these critical roles, the energetics and regulatory mechanisms controlling the T3SS and pa...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Burgess, Jamie L., Burgess, R. Alan, Morales, Yalemi, Bouvang, Jenna M., Johnson, Sean J., Dickenson, Nicholas E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Molecular Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207059/
https://ncbi.nlm.nih.gov/pubmed/27770024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755256
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