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DNA damage in aging, the stem cell perspective

DNA damage is one of the most consistent cellular process proposed to contribute to aging. The maintenance of genomic and epigenomic integrity is critical for proper function of cells and tissues throughout life, and this homeostasis is under constant strain from both extrinsic and intrinsic insults...

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Pubblicato in:Hum Genet
Autori principali: McNeely, Taylor, Leone, Michael, Yanai, Hagai, Beerman, Isabel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980431/
https://ncbi.nlm.nih.gov/pubmed/31324975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-019-02047-z
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