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Evaluating continuous chirality measure as a 3D descriptor in chemoinformatics applied to asymmetric catalysis

Continuous Chirality Measure (CCM) is a computational metric by which to quantify the chirality of a compound. In enantioselective catalysis, prior work has postulated that CCM is correlated to selectivity and can be used to understand which structural features dictate catalyst efficacy. Herein, the...

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Zahrt, Andrew F., Denmark, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980240/
https://ncbi.nlm.nih.gov/pubmed/31983782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2019.02.007
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