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Enantioselective carbene insertion into the N–H bond of benzophenone imine

Efficient enantioselective insertion of α-diazoesters into the N–H bond of N-sp(2)-hybridized benzophenone imine was realized by using Rh(2)(esp)(2) and chiral guanidine cooperative catalysis. Both aliphatic and aromatic substituted α-amino esters were obtained in high yields (up to 99%) and good en...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Yang, Jian, Ruan, Peiran, Yang, Wei, Feng, Xiaoming, Liu, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979361/
https://ncbi.nlm.nih.gov/pubmed/32110317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03354h
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