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Programmable Bivalent Peptide–DNA Locks for pH-Based Control of Antibody Activity
[Image: see text] The ability to control antibody activity by pH has important applications in diagnostics, therapeutic antibody targeting, and antibody-guided imaging. Here, we report the rational design of bivalent peptide–DNA ligands that allow pH-dependent control of antibody activity. Our strat...
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| Udgivet i: | ACS Cent Sci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2019
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978833/ https://ncbi.nlm.nih.gov/pubmed/31989023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00964 |
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