Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons

Teneurins are ancient metazoan cell adhesion receptors that control brain development and neuronal wiring in higher animals. The extracellular C terminus binds the adhesion GPCR Latrophilin, forming a trans-cellular complex with synaptogenic functions. However, Teneurins, Latrophilins, and FLRT prot...

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Gepubliceerd in:Cell
Hoofdauteurs: del Toro, Daniel, Carrasquero-Ordaz, Maria A., Chu, Amy, Ruff, Tobias, Shahin, Meriam, Jackson, Verity A., Chavent, Matthieu, Berbeira-Santana, Miguel, Seyit-Bremer, Goenuel, Brignani, Sara, Kaufmann, Rainer, Lowe, Edward, Klein, Rüdiger, Seiradake, Elena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978801/
https://ncbi.nlm.nih.gov/pubmed/31928845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.12.014
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