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Role of NKCC1 and KCC2 in Epilepsy: From Expression to Function

As a main inhibitory neurotransmitter in the central nervous system, γ-aminobutyric acid (GABA) activates chloride-permeable GABAa receptors (GABAa Rs) and induces chloride ion (Cl(−)) flow, which relies on the intracellular chloride concentration ([Cl(−)](i)) of the postsynaptic neuron. The Na-K-2C...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Neurol
Main Authors: Liu, Ru, Wang, Junling, Liang, Shuli, Zhang, Guojun, Yang, Xiaofeng
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978738/
https://ncbi.nlm.nih.gov/pubmed/32010056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.01407
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