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5-hydroxytryptamine 1F Receptor Agonist Induces Mitochondrial Biogenesis and Promotes Recovery from Spinal Cord Injury

Spinal cord injury (SCI) is characterized by vascular disruption leading to ischemia, decreased oxygen delivery, and loss of mitochondrial homeostasis. This mitochondrial dysfunction results in loss of cellular functions, calcium overload, and oxidative stress. Pharmacological induction of mitochond...

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Bibliografske podrobnosti
izdano v:J Pharmacol Exp Ther
Main Authors: Simmons, Epiphani C., Scholpa, Natalie E., Cleveland, Kristan H., Schnellmann, Rick G.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978694/
https://ncbi.nlm.nih.gov/pubmed/31776207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.262410
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