Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake

INTRODUCTION: Glutamine metabolism is essential for the proliferation of cancer cells. Transported by SLC1A5, a Na(+) dependent transporter, glutamine is absorbed for further use. Recent studies have revealed the anti-tumor effect of berberine. The present study aimed to evaluate the effect of berbe...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Zhang, Pengcheng, Wang, Quancheng, Lin, Zhibin, Yang, Peijun, Dou, Kefeng, Zhang, Ruohan
Format: Artigo
Language:Inglês
Published: Dove 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978679/
https://ncbi.nlm.nih.gov/pubmed/32021249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S235667
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