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Berberine inhibits colorectal tumor growth by suppressing SHH secretion
Hedgehog plays an important role in a wide range of physiological and pathological conditions. Paracrine activation of Hedgehog pathway in stromal cells increases the expression of VEGF, which promotes neovascularization in colorectal cancer and ultimately the growth of colorectal cancer. Berberine...
Tallennettuna:
| Julkaisussa: | Acta Pharmacol Sin |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Springer Singapore
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8209003/ https://ncbi.nlm.nih.gov/pubmed/32958873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-00514-2 |
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