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Telomeres as Therapeutic Targets in Heart Disease
Telomeres are double-stranded repeats of G-rich tandem DNA sequences that gradually shorten with each cell division. Aging, inflammation, and oxidative stress accelerate the process of telomere shortening. Telomerase counteracts this process by maintaining and elongating the telomere length. Patient...
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| Vydáno v: | JACC Basic Transl Sci |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978555/ https://ncbi.nlm.nih.gov/pubmed/31998853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.009 |
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