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Telomeres as Therapeutic Targets in Heart Disease

Telomeres are double-stranded repeats of G-rich tandem DNA sequences that gradually shorten with each cell division. Aging, inflammation, and oxidative stress accelerate the process of telomere shortening. Telomerase counteracts this process by maintaining and elongating the telomere length. Patient...

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Foilsithe in:JACC Basic Transl Sci
Main Authors: Yeh, Jih-Kai, Lin, Mei-Hsiu, Wang, Chao-Yung
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978555/
https://ncbi.nlm.nih.gov/pubmed/31998853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.009
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