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Telomeres as Therapeutic Targets in Heart Disease
Telomeres are double-stranded repeats of G-rich tandem DNA sequences that gradually shorten with each cell division. Aging, inflammation, and oxidative stress accelerate the process of telomere shortening. Telomerase counteracts this process by maintaining and elongating the telomere length. Patient...
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| Publicado no: | JACC Basic Transl Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978555/ https://ncbi.nlm.nih.gov/pubmed/31998853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.009 |
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